CASE 84 (February 2013)

Clinical information

A 46-year-old woman with a history of grade 1 hypertension, about 10 years of evolution, suffered head trauma and brain death. Renal function and urine analysis were normal.

After the family's consent, both kidneys were obtained for transplantation.

A donor renal biopsy was performed. See the images of the renal biopsy.

Figure 1. H&E, X100.

Figure 2. H&E, X100.

Figure 3. H&E, X200.

Figure 4. H&E, X200.

Figure 5. Global glomerulosclerosis: 5 of 145. Masson's trichrome stain, X400.

Figure 6. Hyalinization of afferent and efferent arterioles. PAS, X400.

Figure 7. Methenamine-silver stain, X400.

Figure 8. Three glomeruli with nodules. Methenamine-silver stain, X400.

Figure 9. Masson's trichrome stain, X400.

Figure 9. PAS, X400.

Total global glomerulosclerosis: 3.4%; interstitial fibrosis and tubular atrophy: <5%.

What is your diagnosis?

Would you transplant these kidneys?

See diagnosis and discussion

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