Tervaert TW, Mooyaart AL, Amann K, Cohen AH, Cook HT, Drachenberg CB, Ferrario F, Fogo AB, Haas M, Heer ED, Joh K, Noël LH, Radhakrishnan J, Seshan SV, Bajema IM, Bruijn JA; on behalf of the Renal Pathology Society. Pathologic Classification of Diabetic Nephropathy. J Am Soc Nephrol. 2010 Feb 18. [Epub ahead of print] [PubMed link]
A consensus classification that divides diabetic nephropathy into four hierarchical glomerular lesions with a separate evaluation for degrees of interstitial and vascular involvement. The goal is to differentiate lesions by prognostic severity in a standardized manner that could be easily translated into clinical practice around the world.

Sis B, Mengel M, Haas M, Colvin RB, Halloran PF, Racusen LC, Solez K, Baldwin WM 3rd, Bracamonte ER, Broecker V, Cosio F, Demetris AJ, Drachenberg C, Einecke G, Gloor J, Glotz D, Kraus E, Legendre C, Liapis H, Mannon RB, Nankivell BJ, Nickeleit V, Papadimitriou JC, Randhawa P, Regele H, Renaudin K, Rodriguez ER, Seron D, Seshan S, Suthanthiran M, Wasowska BA, Zachary A, Zeevi A. Banff '09 Meeting Report: Antibody Mediated Graft Deterioration and Implementation of Banff Working Groups. Am J Transplant. 2010 Mar;10(3):464-71. [PubMed link]
The 10th Banff Conference on Allograft Pathology resulted in implementation of six Banff working groups to evaluate clinical relevance and reproducibility of potential changes to the Banff classification.

Gill IS, Aron M, Gervais DA, Jewett MA. Small renal mass. N Engl J Med. 2010 Feb 18;362(7):624-34. [PubMed link]
A good review based on a common clinical problem.

Yang HC, Fogo AB. 'Idiopathic' FSGS: an increasingly obsolete diagnosis? Nephrol Dial Transplant. 2010 Mar;25(3):654-6. [PubMed link]
An editorial comment.

Vieyra MB, Heeger PS. Novel aspects of complement in kidney injury. Kidney Int. 2010 Mar;77(6):495-9. [PubMed link]
Mini review.

Wen YK, Chen ML. The significance of atypical morphology in the changes of spectrum of postinfectious glomerulonephritis. Clin Nephrol. 2010 Mar;73(3):173-9. [PubMed link]
Atypical patterns included focal mesangial proliferation and IgA dominant or co-dominant deposition. There were no statistically significant differences in the clinical presentation and outcome between typical and atypical cases.

Mok C, Cheung T, Lo W. Minimal mesangial lupus nephritis: a systematic review. Scand J Rheumatol. 2010 Feb 18. [Epub ahead of print] [PubMed link]
The authors summarize a literature review on clinical presentation, histological features, treatment, and outcome of minimal change nephropathy in patients with systemic lupus erythematosus.

Polito MG, de Moura LA, Kirsztajn GM. An overview on frequency of renal biopsy diagnosis in Brazil: clinical and pathological patterns based on 9,617 native kidney biopsies. Nephrol Dial Transplant. 2010 Feb;25(2):490-6. [PubMed link]
Focal segmental glomerulosclerosis (24.6%) was the most frequent primary glomerular disease, followed closely by membranous GN (20.7%) and and IgA nephropathy (20.1%).

Pesce F, Schena FP. Worldwide distribution of glomerular diseases: the role of renal biopsy registries. Nephrol Dial Transplant. 2010 Feb;25(2):334-6. [PubMed link] [Free full text]
An Editorial Comment on Dr. Polito et al paper.

Walsh M, Sar A, Lee D, Yilmaz S, Benediktsson H, Manns B, Hemmelgarn B. Histopathologic Features Aid in Predicting Risk for Progression of IgA Nephropathy. Clin J Am Soc Nephrol. 2010 Jan 14. [Epub ahead of print] [PubMed link]
Interstitial fibrosis, glomerular sclerosis, and crescents are independent predictors of outcome.

Ossareh S, Asgari M, Abdi E, Nejad-Gashti H, Ataipour Y, Aris S, Proushani F, Ghorbani G, Hayati F, Ghods AJ. Renal biopsy findings in Iran: case series report from a referral kidney center. Int Urol Nephrol. 2010 Jan 6. [Epub ahead of print] [PubMed link]
Among 1,407 patients with a definite pathologic diagnosis, 1,052 (74.8%) had a primary glomerular disease, 241 (17.2%) had a secondary glomerular disease, 66 (4.6%) had tubular disease, 19 (1.3%) had vascular disease and 7 (0.5%) had end-stage kidney disease.

Franz S, Regeniter A, Hopfer H, Mihatsch M, Dickenmann M. Tubular Toxicity in Sirolimus- and Cyclosporine-Based Transplant Immunosuppression Strategies: An Ancillary Study From a Randomized Controlled Trial.Am J Kidney Dis. 2009 Feb;55(2):335-343. [PubMed link]
Compared with a cyclosporine-based immunosuppression regimen, a sirolimus-based regimen is associated with de novo low-grade glomerular proteinuria, increased excretion of markers associated with tubular damage, and evidence of tubular damage on kidney biopsy.

Perazella MA. Toxic Nephropathies: Core Curriculum 2010. Am J Kidney Dis. 2009 Feb;55(2):399-409.
A concise review.

Chernin G, Heeringa SF, Vega-Warner V, Schoeb DS, Nürnberg P, Hildebrandt F. Adequate use of allele frequencies in Hispanics--a problem elucidated in nephrotic syndrome. Pediatr Nephrol. 2010 Feb;25(2):261-6. [PubMed link]
By genetic sutudies, the authors found that only some families self-identified Hispanic are genetically of Mesoamerican descent, whereas other are of Caucasian descent. The data do suggest that self-identification of ethnicity in Hispanic-American patients is not an adequate basis for diverse studies.

Kim JY, Akalin E, Dikman S, Gagliardi R, Schiano T, Bromberg J, Murphy B, de Boccardo G. The variable pathology of kidney disease after liver transplantation. Transplantation. 2010 Jan 27;89(2):215-21. [PubMed link]
"This study demonstrates universal glomerular abnormalities in kidney biopsies after OLT. The pathology is suggestive of diabetic nephropathy and hypertensive change, but there are also specific glomerular disease processes present. There is little calcineurin inhibitor toxicity in this group".

Matas AJ, Leduc R, Rush D, Cecka JM, Connett J, Fieberg A, Halloran P, Hunsicker L, Cosio F, Grande J, Mannon R, Gourishankar S, Gaston R, Kasiske B. Histopathologic Clusters Differentiate Subgroups Within the Nonspecific Diagnoses of CAN or CR: Preliminary Data from the DeKAF Study. Am J Transplant. 2009 Feb;10(2):315-323. [PubMed link]
The authors used cluster analysis of individual Banff score components to define subgroups.

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